Lai-Hua Xie Selected Research

1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)

8/2020

Iron Overload, Oxidative Stress and Calcium Mishandling in Cardiomyocytes: Role of the Mitochondrial Permeability Transition Pore.

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Lai-Hua Xie Research Topics

Disease

8	Cardiac Arrhythmias (Arrythmia) 01/2023 - 08/2007
8	Cardiomyopathies (Cardiomyopathy) 01/2023 - 10/2017
8	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 11/2022 - 01/2013
5	Iron Overload 01/2023 - 11/2013
5	Ischemia 01/2022 - 09/2015
4	Heart Failure 01/2023 - 02/2011
4	Melanoma (Melanoma, Malignant) 07/2017 - 07/2010
3	Cardiomegaly (Heart Hypertrophy) 01/2023 - 02/2011
3	Fibrosis (Cirrhosis) 11/2022 - 06/2012
3	Hemochromatosis (Bronze Diabetes) 01/2022 - 01/2018
3	Muscular Dystrophies (Muscular Dystrophy) 10/2019 - 08/2015
3	Hypoxia (Hypoxemia) 03/2017 - 09/2015
2	Hypertrophy 01/2023 - 12/2017
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 01/2012
2	Atrial Remodeling 01/2014 - 06/2012
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2023
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 11/2022
1	Cardiotoxicity 01/2022
1	Heart Injuries 01/2022
1	Atherosclerosis 01/2022
1	Cardiac Sudden Death (Sudden Cardiac Arrest) 01/2021
1	Chronic Disease (Chronic Diseases) 01/2021
1	Heart Diseases (Heart Disease) 01/2020
1	Myocardial Infarction 01/2019
1	Neoplasms (Cancer) 01/2019
1	Anemia 01/2018
1	Sickle Cell Anemia (Hemoglobin S Disease) 01/2018
1	Thalassemia 01/2018
1	Ventricular Fibrillation 01/2018
1	Ventricular Premature Complexes (Premature Ventricular Contraction) 01/2018
1	Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain) 09/2015
1	Inflammation (Inflammations) 09/2015
1	Cerebral Infarction 09/2015
1	Stroke (Strokes) 11/2013
1	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2013
1	Hypokalemia 08/2010
1	Neoplasm Metastasis (Metastasis) 07/2010

Drug/Important Bio-Agent (IBA)

8	Connexin 43 (Connexin43)IBA 01/2023 - 08/2015
5	Proteins (Proteins, Gene)FDA Link 11/2022 - 07/2010
5	CalciumIBA 07/2021 - 01/2008
5	sarcolipinIBA 01/2021 - 02/2011
3	IronIBA 01/2023 - 01/2018
3	DystrophinIBA 11/2022 - 01/2013
3	Adenosine Triphosphatases (ATPase)IBA 01/2021 - 02/2011
3	AntioxidantsIBA 01/2021 - 01/2018
3	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 01/2021 - 01/2018
3	Isoproterenol (Isoprenaline)FDA LinkGeneric 01/2018 - 08/2015
3	Glucose (Dextrose)FDA LinkGeneric 03/2017 - 09/2015
2	CatalaseIBA 01/2021 - 01/2018
2	Mitochondrial Permeability Transition PoreIBA 08/2020 - 12/2016
2	Ion Channels (Ion Channel)IBA 01/2018 - 08/2010
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 01/2014
2	Chelating AgentsIBA 01/2018 - 09/2015
2	Oxygen (Dioxygen)IBA 01/2016 - 09/2015
2	erythromycin propionate-N-acetylcysteinateIBA 06/2011 - 07/2010
2	phospholambanIBA 02/2011 - 08/2007
1	mitochondrial calcium uniporterIBA 01/2023
1	CalcineurinIBA 01/2023
1	UtrophinIBA 11/2022
1	Colchicine FDA LinkGeneric 11/2022
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022
1	Adenosine Triphosphate (ATP)IBA 01/2021
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 08/2020
1	ConnexinsIBA 01/2020
1	Phosphotransferases (Kinase)IBA 01/2019
1	Staphylococcal Protein A (Protein A)IBA 01/2019
1	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 01/2018
1	salicylhydroxamic acid (SHAM)IBA 01/2018
1	T-Type Calcium Channels (T-Type Calcium Channel)IBA 01/2018
1	Angiotensin IIIBA 12/2017
1	Calcium-Transporting ATPases (Ca2+ ATPase)IBA 10/2017
1	pyrazoleIBA 07/2017
1	CationsIBA 07/2017
1	Dithionite (Sodium Dithionite)IBA 03/2017
1	Cyclophilins (Cyclophilin)IBA 12/2016
1	Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone (FCCP)IBA 12/2016
1	Interleukin-6 (Interleukin 6)IBA 09/2015
1	N,N,N',N'- tetrakis(2- pyridylmethyl)ethylenediamineIBA 09/2015
1	ZincIBA 09/2015
1	Protein Isoforms (Isoforms)IBA 01/2014
1	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 02/2013
1	Cysteine (L-Cysteine)FDA Link 02/2013
1	Histone Deacetylases (Histone Deacetylase)IBA 02/2013
1	Arginine (L-Arginine)FDA Link 01/2013
1	3,4,5-trimethoxycinnamic acidIBA 01/2013
1	AcidsIBA 01/2013
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2013
1	Extracellular Matrix ProteinsIBA 06/2012
1	CollagenIBA 06/2012
1	Anti-Arrhythmia AgentsIBA 01/2012
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2012
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 08/2010
1	Methyl ester 1,4- dihydro- 2,6- dimethyl- 5- nitro- 4- (2- (trifluoromethyl)phenyl)- 3-Pyridinecarboxylic acidIBA 08/2010
1	Messenger RNA (mRNA)IBA 07/2010
1	Small Interfering RNA (siRNA)IBA 07/2010

Therapy/Procedure

3	Blood Transfusion (Blood Transfusions) 08/2020 - 11/2013
2	Therapeutics 11/2022 - 01/2018
1	Induced Hypothermia 01/2018
1	Oral Administration 01/2013
1	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2013